ARG63192
anti-DUSP8 / HVH5 antibody
anti-DUSP8 / HVH5 antibody for Western blot and Human,Mouse,Rat
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes DUSP8 / HVH5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Cow |
| 应用 | WB |
| 特异性 | This antibody is also expected to recognise the hypothetical human protein similar to dual specificity phosphatase 8 (XM_114902), which is virtually identical. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DUSP8 / HVH5 |
| 抗原物种 | Human |
| 抗原 | AGDRLPRKVMDAK-C |
| 偶联标记 | Un-conjugated |
| 別名 | EC 3.1.3.48; EC 3.1.3.16; HVH-5; HB5; HVH8; Dual specificity protein phosphatase hVH-5; C11orf81; Dual specificity protein phosphatase 8 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O09112 Mouse Dual specificity protein phosphatase 8 Swiss-port # Q13202 Human Dual specificity protein phosphatase 8 |
|---|---|
| 背景介绍 | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 66 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG63192 anti-DUSP8 / HVH5 antibody WB image
Western Blot: Human Heart lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63192 anti-DUSP8 / HVH5 antibody at 2 µg/ml dilution.
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ARG63192 anti-DUSP8 / HVH5 antibody WB image
Western blot: 35 µg of Human cerebellum (A), Mouse brain (B) and Rat brain (C) lysates (in RIPA buffer) stained with ARG63192 anti-DUSP8 / HVH5 antibody at 2 µg/ml dilution and incubated at RT for 1 hour.
