ARG59616
anti-DUSP5 antibody
anti-DUSP5 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DUSP5 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DUSP5 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 315-384 of Human DUSP5 (NP_004410.3). |
| 偶联标记 | Un-conjugated |
| 別名 | EC 3.1.3.16; HVH3; Dual specificity protein phosphatase 5; Dual specificity protein phosphatase hVH3; EC 3.1.3.48; DUSP |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Raji | ||||
| 实际分子量 | 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q16690 Human Dual specificity protein phosphatase 5 |
|---|---|
| 基因名称 | DUSP5 |
| 全名 | dual specificity phosphatase 5 |
| 背景介绍 | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008] |
| 生物功能 | Displays phosphatase activity toward several substrates. The highest relative activity is toward ERK1. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 42 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59616 anti-DUSP5 antibody WB image
Western blot: 25 µg of Raji cell lysate stained with ARG59616 anti-DUSP5 antibody at 1:1000 dilution.
