ARG45755
anti-DUBA antibody
anti-DUBA antibody for ICC/IF,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DUBA |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DUBA |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human DUBA. |
| 偶联标记 | Un-conjugated |
| 別名 | OTUD5; OTU Deubiquitinase 5; DUBA; OTU Domain-Containing Protein 5; Deubiquitinating Enzyme A; OTU Domain Containing 5; Deubiquitinase A; DKFZp761A052; Deubiquinating Enzyme A; EC 3.4.19.12; MCAND |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 75 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | OTUD5 |
| 全名 | OTU Deubiquitinase 5 |
| 背景介绍 | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] |
| 生物功能 | Deubiquitinating enzyme that functions as a negative regulator of the innate immune system. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45755 anti-DUBA antibody ICC/IF image
Immunofluorescence: A431 stained with ARG45755 anti-DUBA antibody at 5 μg/ml dilution.
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ARG45755 anti-DUBA antibody WB image
Western blot: 293T stained with ARG45755 anti-DUBA antibody at 0.5 μg/ml dilution.
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ARG45755 anti-DUBA antibody WB image
Western blot: Rat liver stained with ARG45755 anti-DUBA antibody at 0.5 μg/ml dilution.
