ARG58512
anti-DRD1 / Dopamine Receptor D1 antibody
anti-DRD1 / Dopamine Receptor D1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DRD1 / Dopamine Receptor D1 |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Hm |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DRD1 / Dopamine Receptor D1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to a sequence in the middle region of Human DRD1 (221-242aa AQKQIRRIAALERAAVHAKNCQ), different from the related Rat and Mouse sequences by one amino acid. |
| 偶联标记 | Un-conjugated |
| 別名 | DADR; DRD1A; D(1A) dopamine receptor; Dopamine D1 receptor |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DRD1 |
| 全名 | dopamine receptor D1 |
| 背景介绍 | This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. [UniProt] |
| 预测分子量 | 49 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58512 anti-DRD1 / Dopamine Receptor D1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat brain stained with ARG58512 anti-DRD1 / Dopamine Receptor D1 antibody.
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ARG58512 anti-DRD1 / Dopamine Receptor D1 antibody WB image
Western blot: Rat testis, Rat brain, U87 and HeLa lysates stained with ARG58512 anti-DRD1 / Dopamine Receptor D1 antibody.
