ARG44814
anti-DRAXIN antibody
anti-DRAXIN antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes DRAXIN |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | DRAXIN |
| 抗原物种 | Human |
| 抗原表位 | GALAPGTPAR NLPENHIDLP GPALWTPQAS HHRRRGPGKK EWGPGLPSQA QDGAVVTATR QASRLPEAEG LLPEQSPAGL LQDKDLLLGL ALPYPEKENR PPGWERTRKR SREHKRRRDR LRLHQGRALV RGPSSLMKKA ELSEAQVLDA AMEESSTSLA PTMFFLTTFE AAPATEESLI LPVTSLRPQQ AQPRSDGEVM PTLDMALFDW TDYEDLKPDG WPSAKKKEKH RGKLSSDGNE TSPAEGEPCD HHQDCLPGTC CDLREHLCTP HNRGLNNKCF DDCMCVEGLR CYAKFHRNRR VTRRKGRCVE PETANGDQGS FINV |
| 偶联标记 | Un-conjugated |
| 別名 | DRAXIN; Dorsal Inhibitory Axon Guidance Protein; Neucrin; Dorsal Repulsive Axon Guidance Protein; C1orf187; Neural Tissue-Specific Cysteine-Rich Protein; FLJ34999; Draxin; Chromosome 1 Open Reading Frame 187; AGPA3119; UNQ3119 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DRAXIN |
| 全名 | Dorsal Inhibitory Axon Guidance Protein |
| 背景介绍 | Predicted to be involved in negative regulation of canonical Wnt signaling pathway; negative regulation of neuron projection development; and nervous system development. Predicted to act upstream of or within negative regulation of axon extension and negative regulation of neuron apoptotic process. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. [Uniprot] |
| 细胞定位 | Secreted. [Uniprot] |
| 翻译后修饰 | Glycoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44814 anti-DRAXIN antibody IHC-P image
Immunohistochemistry: Human brain stained with ARG44814 anti-DRAXIN antibody at 5 µg/mL dilution.
