ARG40784
anti-DPP10 antibody
anti-DPP10 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DPP10 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DPP10 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 150-177 of Human DPP10. |
| 偶联标记 | Un-conjugated |
| 別名 | Inactive dipeptidyl peptidase 10; Dipeptidyl peptidase-like protein 2; DPRP3; DPPY; DPRP-3; Dipeptidyl peptidase IV-related protein 3; DPP X; DPL2; Dipeptidyl peptidase X |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse liver | ||||||
| 实际分子量 | ~ 91 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DPP10 |
| 全名 | dipeptidyl-peptidase 10 (non-functional) |
| 背景介绍 | This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity. [UniProt] |
| 细胞定位 | Membrane; Single-pass type II membrane protein. [UniProt] |
| 预测分子量 | 91 kDa |
| 翻译后修饰 | N-glycosylation is important for cell surface expression, specially at Asn-257, which is crucial. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40784 anti-DPP10 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain tissue stained with ARG40784 anti-DPP10 antibody.
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ARG40784 anti-DPP10 antibody WB image
Western blot: 35 µg of Mouse liver lysate stained with ARG40784 anti-DPP10 antibody.
