ARG46428
anti-DPF2 / REQ antibody
anti-DPF2 / REQ antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DPF2 / REQ |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DPF2 / REQ |
| 抗原物种 | Human |
| 抗原 | A 18 amino acid synthetic peptide within the last 50 amino acids of human DPF2 / REQ. |
| 偶联标记 | Un-conjugated |
| 別名 | D4, zinc and double PHD fingers family 2; REQUIEM; REQ; UBID4; ubi-d4; BAF45D; REQ; Zinc finger protein ubi-d4; Apoptosis response zinc finger protein; DPF2 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -478°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DPF2 |
| 全名 | D4, zinc and double PHD fingers family 2 |
| 背景介绍 | The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:27775714, PubMed:28533407). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway (PubMed:20460684). [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 44 kDa |
| 翻译后修饰 | Phosphoprotein; Isopeptide bond; Ubl conjugation. [UniProt] |
