ARG56480

anti-DP1 Receptor antibody

anti-DP1 Receptor antibody for ICC/IF,Western blot and Human,Mouse,Rat

publication_link 参考文献1

概述

产品描述 Rabbit Polyclonal antibody recognizes DP1 Receptor
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 DP1 Receptor
抗原物种 Mouse
抗原 Synthetic peptide around the N-terminus of Mouse DP1 Receptor.
偶联标记 Un-conjugated
別名 PTGDR1; AS1; DP1; ASRT1; PGD receptor; Prostanoid DP receptor; Prostaglandin D2 receptor; DP; PGD2 receptor

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:200
WB1:200
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol and 0.1% BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 19214 Mouse PTGDR

GeneID: 498475 Rat PTGDR

GeneID: 5729 Human PTGDR

基因名称 Ptgdr
全名 prostaglandin D receptor
背景介绍 This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein is reported to be a receptor for prostaglandin D2, which is a mediator of allergic inflammation and allergic airway inflammation in asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
生物功能 Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). [UniProt]
预测分子量 40 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG56480 anti-DP1 Receptor antibody WB image

    Western blot: 1) Precision Plus Protein Standard, 2) 10 µg of HT-29 cell lysate, 3) 20 µg of HT-29 cell lysate, and 4) 40 µg of HT-29 cell lysate stained with ARG56480 anti-DP1 Receptor antibody.

文献引用

L-PGDS–PGD2–DP1 Axis Regulates Phagocytosis by CD36+ MGs/MΦs That Are Exclusively PresentWithin Ischemic Areas After Stroke

IHC-P / Mouse

Takayuki Nakagomi et al.
Cells.,  (2024)

publication_link

 

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