ARG59901
anti-DOK4 antibody
anti-DOK4 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DOK4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DOK4 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 240-326 of Human DOK4 (NP_060580.2). |
| 偶联标记 | Un-conjugated |
| 別名 | IRS5; Docking protein 4; Insulin receptor substrate 5; Downstream of tyrosine kinase 4; IRS-5 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | MCF7 | ||||||||
| 实际分子量 | 37 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DOK4 |
| 全名 | docking protein 4 |
| 生物功能 | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt] |
| 预测分子量 | 37 kDa |
| 翻译后修饰 | Phosphorylated on tyrosine residues in response to insulin, IGF1 or RET stimulation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG59901 anti-DOK4 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG59901 anti-DOK4 antibody.
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ARG59901 anti-DOK4 antibody WB image
Western blot: 25 µg of MCF7 cell lysate stained with ARG59901 anti-DOK4 antibody at 1:1000 dilution.
