ARG45243
anti-DOCK4 antibody
anti-DOCK4 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Polyclonal antibody recognizes DOCK4 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DOCK4 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human DOCK4. |
| 偶联标记 | Un-conjugated |
| 別名 | DOCK4; Dedicator Of Cytokinesis 4; KIAA0716; Dedicator Of Cytokinesis Protein 4; FLJ34238 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 250 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8N1I0 Human Dedicator of cytokinesis protein 4 |
|---|---|
| 基因名称 | DOCK4 |
| 全名 | Dedicator Of Cytokinesis 4 |
| 背景介绍 | This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. [UniProt] |
| 细胞定位 | Cell membrane ; Cell projection ; Cytoplasm ; Membrane. [UniProt] |
| 预测分子量 | 225 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG45243 anti-DOCK4 antibody IHC-P image
Immunohistochemistry: Human skeletal muscle stained with ARG45243 anti-DOCK4 antibody at 2 μg/ml dilution.
-
ARG45243 anti-DOCK4 antibody WB image
Western blot: 293T stained with ARG45243 anti-DOCK4 antibody at 0.5 μg/ml dilution.
-
ARG45243 anti-DOCK4 antibody FACS image
Flow Cytometry: SiHa stained with ARG45243 anti-DOCK4 antibody at 1 µg/10^6 cells dilution.
-
ARG45243 anti-DOCK4 antibody WB image
Western blot: L6 stained with ARG45243 anti-DOCK4 antibody at 0.5 μg/ml dilution.
