ARG45722
anti-DNAJC6 antibody
anti-DNAJC6 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DNAJC6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DNAJC6 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human DNAJC6. |
| 偶联标记 | Un-conjugated |
| 別名 | DNAJC6; DnaJ Heat Shock Protein Family (Hsp40) Member C6; KIAA0473; Auxilin; PARK19; DnaJ (Hsp40) Homolog, Subfamily C, Member 6; Putative Tyrosine-Protein Phosphatase Auxilin; DnaJ (Hsp40) Homolog, Subfamily B, Member 6; DnaJ Homolog Subfamily C Member 6; EC 3.1.3.-; DJC6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 120 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O75061 Human Putative tyrosine-protein phosphatase auxilin Swiss-port # Q80TZ3 Mouse Putative tyrosine-protein phosphatase auxilin |
|---|---|
| 基因名称 | DNAJC6 |
| 全名 | DnaJ Heat Shock Protein Family (Hsp40) Member C6 |
| 背景介绍 | DNAJC6 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain (Ohtsuka and Hata, 2000 [PubMed 11147971]).[supplied by OMIM, Mar 2008] |
| 生物功能 | May act as a protein phosphatase and/or a lipid phosphatase. Co-chaperone that recruits HSPA8/HSC70 to clathrin-coated vesicles (CCVs) and promotes the ATP-dependent dissociation of clathrin from CCVs and participates in clathrin-mediated endocytosis of synaptic vesicles and their recycling and also in intracellular trafficking. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle. [UniProt] |
| 预测分子量 | 100 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45722 anti-DNAJC6 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45722 anti-DNAJC6 antibody at 5 μg/ml dilution.
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ARG45722 anti-DNAJC6 antibody WB image
Western blot: HEL stained with ARG45722 anti-DNAJC6 antibody at 0.5 μg/ml dilution.
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ARG45722 anti-DNAJC6 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45722 anti-DNAJC6 antibody at 2 μg/ml dilution.
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ARG45722 anti-DNAJC6 antibody WB image
Western blot: PC-12 stained with ARG45722 anti-DNAJC6 antibody at 0.5 μg/ml dilution.
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ARG45722 anti-DNAJC6 antibody WB image
Western blot: Mouse brain stained with ARG45722 anti-DNAJC6 antibody at 0.5 μg/ml dilution.
