ARG41019

anti-DNAJC19 antibody

anti-DNAJC19 antibody for ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes DNAJC19
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 DNAJC19
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 1-116 of Human DNAJC19 (NP_660304.1).
偶联标记 Un-conjugated
別名 TIM14; TIMM14; PAM18; Mitochondrial import inner membrane translocase subunit TIM14; DnaJ homolog subfamily C member 19

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 HT1080
实际分子量 12 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 131118 Human DNAJC19

GeneID: 67713 Mouse DNAJC19

Swiss-port # Q96DA6 Human Mitochondrial import inner membrane translocase subunit TIM14

Swiss-port # Q9CQV7 Mouse Mitochondrial import inner membrane translocase subunit TIM14

基因名称 DNAJC19
全名 DnaJ (Hsp40) homolog, subfamily C, member 19
背景介绍 The protein encoded by this gene is thought to be part of a complex involved in the ATP-dependent transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. Defects in this gene are a cause of 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 2, 6, 10, 14 and 19. [provided by RefSeq, Jan 2012]
生物功能 Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). [UniProt]
细胞定位 Mitochondrion inner membrane; Single-pass membrane protein. [UniProt]
预测分子量 12 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG41019 anti-DNAJC19 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG41019 anti-DNAJC19 antibody at 1:100 dilution.

  • ARG41019 anti-DNAJC19 antibody WB image

    Western blot: 25 µg of HT1080 cell lysate stained with ARG41019 anti-DNAJC19 antibody at 1:3000 dilution through one-step method.