ARG55228
anti-DLK1 antibody
anti-DLK1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DLK1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DLK1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 368-402 (C-terminus) of Human DLK1. |
| 偶联标记 | Un-conjugated |
| 別名 | Delta1; ZOG; DLK; FA1; DLK-1; pG2; Pref-1; PREF1; Protein delta homolog 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse skeletal muscle |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DLK1 |
| 全名 | delta-like 1 homolog (Drosophila) |
| 背景介绍 | This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010] |
| 生物功能 | May have a role in neuroendocrine differentiation. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein |
| 研究领域 | Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. |
检测图片 (3) Click the Picture to Zoom In
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ARG55228 anti-DLK1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human placenta tissue stained with ARG55228 anti-DLK1 antibody at 1:25 dilution.
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ARG55228 anti-DLK1 antibody WB image
Western blot: 20 µg of Mouse skeletal muscle lysate stained with ARG55228 anti-DLK1 antibody at 1:1000 dilution.
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ARG55228 anti-DLK1 antibody FACS image
Flow Cytometry: HepG2 cells stained with ARG55228 anti-DLK1 antibody (right histogram) at 1:25 dilution or without primary antibodies (left histogram), followed by incubation with Alexa Fluor® 488 labelled secondary antibody.
