ARG45064
anti-DISC1 antibody
anti-DISC1 antibody for Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DISC1 |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DISC1 |
| 抗原物种 | Mouse |
| 抗原 | DISC1 synthetic peptide containing amino acid residues from the C-terminus of mouse DISC1. This peptide sequence is well conserved in rat DISC1, but has 7 amino acid differences with the conserved site in human DISC1. |
| 偶联标记 | Un-conjugated |
| 別名 | DISC1; DISC1 Scaffold Protein; Disrupted In Schizophrenia 1 Protein; Disrupted In Schizophrenia 1; C1orf136; KIAA0457; SCZD9 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q810H6 Rat Disrupted in schizophrenia 1 homolog Swiss-port # Q811T9 Mouse Disrupted in schizophrenia 1 homolog |
|---|---|
| 基因名称 | DISC1 |
| 全名 | DISC1 Scaffold Protein |
| 背景介绍 | This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a role, together with PCNT, in the microtubule network formation. [Uniprot] |
| 细胞定位 | Cytoplasm, Cytoskeleton, Microtubule, Mitochondrion, Synapse. [Uniprot] |
| 预测分子量 | 94 kDa |
| 翻译后修饰 | Isopeptide bond, Ubl conjugation. [Uniprot] |
