ARG41176
anti-DHRS9 antibody
anti-DHRS9 antibody for ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DHRS9 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DHRS9 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 18-319 of Human DHRS9 (NP_001135743.1). |
| 偶联标记 | Un-conjugated |
| 別名 | Tracheobronchial epithelial cell-specific retinol dehydrogenase; 3-alpha-HSD; Short-chain dehydrogenase/reductase retSDR8; RDH-TBE; NADP-dependent retinol dehydrogenase/reductase; 3-alpha hydroxysteroid dehydrogenase; Dehydrogenase/reductase SDR family member 9; RDH15; RDHL; RDH-E2; RETSDR8; Short chain dehydrogenase/reductase family 9C member 4; Retinol dehydrogenase 15; RDHTBE; EC 1.1.-.-; SDR9C4; 3ALPHA-HSD |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | THP-1 | ||||||
| 实际分子量 | 33 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DHRS9 |
| 全名 | dehydrogenase/reductase (SDR family) member 9 |
| 背景介绍 | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| 生物功能 | 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH. [UniProt] |
| 细胞定位 | Microsome membrane. Endoplasmic reticulum membrane. Note=Associated with microsomal membranes. [UniProt] |
| 预测分子量 | 35 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41176 anti-DHRS9 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG41176 anti-DHRS9 antibody.
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ARG41176 anti-DHRS9 antibody WB image
Western blot: 25 µg of THP-1 cell lysate stained with ARG41176 anti-DHRS9 antibody at 1:1000 dilution.
