ARG42783
anti-DEGS1 / MLD antibody
anti-DEGS1 / MLD antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DEGS1 / MLD |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DEGS1 / MLD |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human DEGS1 / MLD. |
| 偶联标记 | Un-conjugated |
| 別名 | MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1; Sphingolipid delta(4)-desaturase DES1; EC 1.14.-.-; Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; Membrane lipid desaturase |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa | ||||
| 实际分子量 | ~ 36 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O15121 Human Sphingolipid delta(4)-desaturase DES1 |
|---|---|
| 基因名称 | DEGS1 |
| 全名 | delta(4)-desaturase, sphingolipid 1 |
| 背景介绍 | This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010] |
| 生物功能 | Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). [UniProt] |
| 细胞定位 | Mitochondrion. Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Lipid-anchor. [UniProt] |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | Myristoylation can target the enzyme to the mitochondria leading to an increase in ceramide levels. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42783 anti-DEGS1 / MLD antibody WB image
Western blot: HeLa cell lysate stained with ARG42783 anti-DEGS1 / MLD antibody at 1:1000 dilution.
