ARG46120
anti-DEDD2 antibody
anti-DEDD2 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DEDD2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DEDD2 |
| 抗原物种 | Human |
| 抗原 | A 11 amino acid synthetic peptide within the first 50 amino acids of human DEDD2. |
| 偶联标记 | Un-conjugated |
| 別名 | death effector domain containing 2; DEDD2; FLAME-3; FLAME3; PSEC0004; DED-containing protein FLAME-3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -170°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8QZV0 Mouse DNA-binding death effector domain-containing protein 2 Swiss-port # Q8WXF8 Human DNA-binding death effector domain-containing protein 2 |
|---|---|
| 基因名称 | DEDD2 |
| 全名 | death effector domain containing 2 |
| 背景介绍 | This gene encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
| 生物功能 | May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 36 kDa |
