ARG58482
anti-DDOST antibody
anti-DDOST antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DDOST |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DDOST |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 40-300 of Human DDOST (NP_005207.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Oligosaccharyl transferase 48 kDa subunit; CDG1R; OST48; OKSWcl45; EC 2.4.99.18; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; OST; AGER1; DDOST 48 kDa subunit; WBP1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | U-87MG | ||||||
| 实际分子量 | 51 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DDOST |
| 全名 | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) |
| 背景介绍 | This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008] |
| 生物功能 | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. [UniProt] |
| 细胞定位 | Endoplasmic reticulum membrane, Single-pass type I membrane protein,. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG58482 anti-DDOST antibody WB image
Western blot: 25 µg of U-87MG cell lysate stained with ARG58482 anti-DDOST antibody at 1:1000 dilution.
