ARG63442
anti-DBNL / HIP55 antibody
anti-DBNL / HIP55 antibody for Western blot and Human
Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes DBNL / HIP55 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog |
| 应用 | WB |
| 特异性 | This antibody is expected to recognise all reported isoforms (NP_054782.2; NP_001014436.1; NP_001116428.1) |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DBNL / HIP55 |
| 抗原物种 | Human |
| 抗原 | AANLSRNGPALQE-C |
| 偶联标记 | Un-conjugated |
| 別名 | SH3P7; HIP55; SH3 domain-containing protein 7; ABP1; Cervical SH3P7; Drebrin-F; HPK1-interacting protein of 55 kDa; Drebrin-like protein; HIP-55; Cervical mucin-associated protein |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DBNL |
| 全名 | drebrin-like |
| 生物功能 | Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 48 kDa |
| 翻译后修饰 | Degraded by caspases during apoptosis. |
检测图片 (2) Click the Picture to Zoom In
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ARG63442 anti-DBNL / HIP55 antibody WB image
Western blot: Jurkat lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63442 anti-DBNL / HIP55 antibody at 1 µg/ml dilution.
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ARG63442 anti-DBNL / HIP55 antibody WB image
Western blot: 35 µg of Human peripheral blood mononucleocyte lysate (in RIPA buffer) stained with ARG63442 anti-DBNL / HIP55 antibody at 0.03 µg/ml dilution and incubated at RT for 1 hour.
