ARG45814
anti-DBF4 antibody
anti-DBF4 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DBF4 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DBF4 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human DBF4. |
| 偶联标记 | Un-conjugated |
| 別名 | DBF4; DBF4-CDC7 Kinase Regulatory Subunit; ZDBF1; DBF4A; ASK; Activator Of S Phase Kinase; Chif; DBF4-Type Zinc Finger-Containing Protein 1; Zinc Finger, DBF-Type Containing 1; Regulatory Subunit Of DDK; Protein DBF4 Homolog A; DBF4 Zinc Finger A; Chiffon Homolog A; Chiffon Homolog (Drosophila); DBF4 Homolog (S. Cerevisiae); DBF4 Zinc Finger; DBF4 Homolog |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | DBF4 |
| 全名 | DBF4-CDC7 Kinase Regulatory Subunit |
| 背景介绍 | Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body. [provided by Alliance of Genome Resources, Feb 2025] |
| 生物功能 | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 77 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45814 anti-DBF4 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45814 anti-DBF4 antibody at 5 μg/ml dilution.
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ARG45814 anti-DBF4 antibody WB image
Western blot: HepG2 stained with ARG45814 anti-DBF4 antibody at 0.5 μg/ml dilution.
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ARG45814 anti-DBF4 antibody FACS image
Flow Cytometry: Raji stained with ARG45814 anti-DBF4 antibody at 1 µg/10^6 cells dilution.
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ARG45814 anti-DBF4 antibody WB image
Western blot: PC-12 stained with ARG45814 anti-DBF4 antibody at 0.5 μg/ml dilution.
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ARG45814 anti-DBF4 antibody WB image
Western blot: NIH/3T3 stained with ARG45814 anti-DBF4 antibody at 0.5 μg/ml dilution.
