ARG44853
anti-Cytokeratin 3 / CK3 antibody
anti-Cytokeratin 3 / CK3 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Cytokeratin 3 / CK3 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | Cytokeratin 3 / CK3 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | KRT3; Keratin 3; K3; Keratin, Type II Cytoskeletal 3; CK3; Type-II Keratin Kb3; 65 KDa Cytokeratin; Cytokeratin 3; CK-3; Keratin 3, Type II; Cytokeratin-3; Keratin-3; MECD2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purified. |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KRT3 |
| 全名 | Keratin 3 |
| 背景介绍 | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008] |
| 生物功能 | There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa). [Uniprot] |
| 细胞定位 | Intermediate filament, Keratin. [Uniprot] |
| 翻译后修饰 | Methylation, Phosphoprotein. [Uniprot] |
检测图片 (1) Click the Picture to Zoom In
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ARG44853 anti-Cytokeratin 3 / CK3 antibody IHC-P image
Immunohistochemistry: skin stained with ARG44853 anti-Cytokeratin 3 / CK3 antibody at 7.5 µg/mL dilution.
