anti-Cytokeratin 14 antibody [SQab18101]

anti-Cytokeratin 14 antibody [SQab18101] for IHC-Formalin-fixed paraffin-embedded sections and Human


产品描述 Recombinant Rabbit Monoclonal antibody [SQab18101] recognizes Cytokeratin 14
反应物种 Hu
应用 IHC-P
宿主 Rabbit
克隆 Monoclonal
克隆号 SQab18101
同位型 IgG
靶点名称 Cytokeratin 14
抗原物种 Human
抗原 Synthetic peptide within aa. 372-472 of Human Cytokeratin 14.
偶联标记 Un-conjugated
別名 K14; CK-14; Cytokeratin-14; Keratin, type I cytoskeletal 14; EBS3; EBS4; NFJ; Keratin-14; CK14


应用 推荐稀释比
IHC-P1:100 - 1:200
应用说明 IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT for 30 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Purification with Protein A.
缓冲液 PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂 0.01% Sodium azide
稳定剂 40% Glycerol and 0.05% BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 3861 Human KRT14

Swiss-port # P02533 Human Keratin, type I cytoskeletal 14

基因名称 KRT14
全名 keratin 14, type I
背景介绍 This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]
生物功能 The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. [UniProt]
产品亮点 Related products:
Anti-Rabbit IgG secondary antibodies;
Related news:
Cancer Pathology Markers (SQ clones)
预测分子量 52 kDa
翻译后修饰 A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus.

Ubiquitinated by the BCR(KLHL24) E3 ubiquitin ligase complex. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG66351 anti-Cytokeratin 14 antibody [SQab18101] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded esophagus tissue stained with ARG66351 anti-Cytokeratin 14 antibody [SQab18101]. Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).