ARG44693
anti-Cytokeratin 14 antibody
anti-Cytokeratin 14 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Cytokeratin 14 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | Cytokeratin 14 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | K14; CK-14; Cytokeratin-14; Keratin, type I cytoskeletal 14; EBS3; EBS4; NFJ; Keratin-14; CK14 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KRT14 |
| 全名 | keratin 14, type I |
| 背景介绍 | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008] |
| 生物功能 | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern. [UniProt] |
| 预测分子量 | 52 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG44693 anti-Cytokeratin 14 antibody IHC-P image
Immunohistochemistry: Human esophageal squamous cell carcinoma stained with ARG44693 anti-Cytokeratin 14 antibody at 2 µg/mL dilution.
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ARG44693 anti-Cytokeratin 14 antibody WB image
Western blot: A431 stained with ARG44693 anti-Cytokeratin 14 antibody at 1 µg/mL dilution.
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ARG44693 anti-Cytokeratin 14 antibody IP image
Immunoprecipitation: A431 lysate immunoprecipitated with 2.5 µg of ARG44693 anti-Cytokeratin 14 antibody.
