ARG66490
anti-Cytokeratin 13 antibody
anti-Cytokeratin 13 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes Cytokeratin 13 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1, kappa |
| 靶点名称 | Cytokeratin 13 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Cytokeratin 13. |
| 偶联标记 | Un-conjugated |
| 別名 | K13; Keratin, type I cytoskeletal 13; CK-13; Cytokeratin-13; WSN2; CK13; Keratin-13 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Citric acid buffer (pH 6.0) was used. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KRT13 |
| 全名 | keratin 13, type I |
| 背景介绍 | The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008] |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | O-glycosylated; glycans consist of single N-acetylglucosamine residues. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG66490 anti-Cytokeratin 13 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human transitional cell carcinoma stained with ARG66490 anti-Cytokeratin 13 antibody at 1:200 (4°C, overnight). Antigen Retrieval: Citric acid buffer (pH 6.0) was used.
-
ARG66490 anti-Cytokeratin 13 antibody WB image
Western blot: 30 µg of A431, HeLa (negative control) and MCF7 (negative control) whole cell lysates stained with ARG66490 anti-Cytokeratin 13 antibody at 1:1000 dilution.
-
ARG66490 anti-Cytokeratin 13 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human squamous cell lung carcinoma stained with ARG66490 anti-Cytokeratin 13 antibody at 1:200 (4°C, overnight). Antigen Retrieval: Citric acid buffer (pH 6.0) was used.
-
ARG66490 anti-Cytokeratin 13 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human tonsil stained with ARG66490 anti-Cytokeratin 13 antibody at 1:200 (4°C, overnight). Antigen Retrieval: Citric acid buffer (pH 6.0) was used.
