anti-Cytokeratin 10 antibody [SQab1884]

anti-Cytokeratin 10 antibody [SQab1884] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human


产品描述 Recombinant Rabbit Monoclonal antibody [SQab1884] recognizes Cytokeratin 10
反应物种 Hu
宿主 Rabbit
克隆 Monoclonal
克隆号 SQab1884
同位型 IgG
靶点名称 Cytokeratin 10
抗原物种 Human
抗原 Synthetic peptide around the C-terminus of Human Cytokeratin 10.
偶联标记 Un-conjugated
別名 KPP; K10; CK-10; BIE; Keratin, type I cytoskeletal 10; Cytokeratin-10; CK10; BCIE; Keratin-10; EHK


应用 推荐稀释比
FACS1:50 - 1:200
IHC-P1:6400 - 1:12800
应用说明 IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Purification with Protein A.
缓冲液 PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂 0.01% Sodium azide
稳定剂 40% Glycerol and 0.05% BSA
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 3858 Human KRT10

Swiss-port # P13645 Human Keratin, type I cytoskeletal 10

基因名称 KRT10
全名 keratin 10, type I
背景介绍 Cytokeratin 10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
生物功能 Cytokeratin 10 plays a role in the establishment of the epidermal barrier on plantar skin.

(Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.

(Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur. [UniProt]
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预测分子量 59 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG66336 anti-Cytokeratin 10 antibody [SQab1884] FACS image

    Flow Cytometry: HeLa cells were fixed with 4% paraformaldehyde for 10 mins. The cells were stained with ARG66336 anti-Cytokeratin 10 antibody [SQab1884] (red) at 1:200 dilution in 1x PBS/1% BSA for 30 min at RT, followed by Alexa Fluor® 488 labelled secondary antibody. Unlabelled sample (black) was used as a control.

  • ARG66336 anti-Cytokeratin 10 antibody [SQab1884] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human cervix tissue stained with ARG66336 anti-Cytokeratin 10 antibody [SQab1884] at 1:12,800 dilution. Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0.