ARG54107
anti-Cytochrome P450 17A1 antibody
anti-Cytochrome P450 17A1 antibody for Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody recognizes CYP17A1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | Cytochrome P450 17A1 |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human Cytochrome P450 17A1 protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
| 別名 | CYP17; P450C17; Cytochrome P450-C17; S17AH; Cytochrome P450c17; CPT7; Steroid 17-alpha-hydroxylase/17,20 lyase; Steroid 17-alpha-monooxygenase; EC 4.1.2.30; CYPXVII; 17-alpha-hydroxyprogesterone aldolase; EC 1.14.99.9; Cytochrome P450 17A1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 60 kDa |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | Ascites |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P05093 Human Steroid 17-alpha-hydroxylase/17,20 lyase |
|---|---|
| 基因名称 | CYP17A1 |
| 全名 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| 背景介绍 | Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione.Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.Involved in sexual development during fetal life and at puberty. |
| 生物功能 | Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. [UniProt] |
| 细胞定位 | Membrane. |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 57 kDa |
| 翻译后修饰 | Phosphorylation is necessary for 17,20-lyase, but not for 17-alpha-hydroxylase activity. |
检测图片 (1) Click the Picture to Zoom In
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ARG54107 anti-Cytochrome P450 17A1 antibody WB image
Western blot: A549 cell lysate stained with ARG54107 anti-Cytochrome P450 17A1 antibody at 1:1000 dilution.
