ARG41442
anti-Cyclin E2 antibody
anti-Cyclin E2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cyclin E2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Cyclin E2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human Cyclin E2. |
| 偶联标记 | Un-conjugated |
| 別名 | CYCE2; G1/S-specific cyclin-E2 |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | HeLa | ||||||||||
| 实际分子量 | ~ 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CCNE2 |
| 全名 | cyclin E2 |
| 背景介绍 | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008] |
| 生物功能 | Essential for the control of the cell cycle at the late G1 and early S phase. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 47 kDa |
| 翻译后修饰 | Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
-
ARG41442 anti-Cyclin E2 antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG41442 anti-Cyclin E2 antibody.
-
ARG41442 anti-Cyclin E2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast carcinoma tissue stained with ARG41442 anti-Cyclin E2 antibody.
-
ARG41442 anti-Cyclin E2 antibody WB image
Western blot: HeLa cell lysate stained with ARG41442 anti-Cyclin E2 antibody.
