ARG20534
anti-Cpn 10 antibody
anti-Cpn 10 antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat,Bovine,Dog,Guinea pig,Pig,Rabbit,Sheep,Xenopus laevis
Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cpn 10 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bov, Dog, Gpig, Pig, Rb, Sheep, Xenopus laevis |
| 应用 | ELISA, ICC/IF, IHC-P, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 靶点名称 | Cpn 10 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 91-101 of Human Cpn10. |
| 偶联标记 | Un-conjugated |
| 別名 | HSP10; 10 kDa chaperonin; CPN10; Early-pregnancy factor; Hsp10; GROES; EPF; Chaperonin 10; 10 kDa heat shock protein, mitochondrial |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.3) and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HSPE1 |
| 全名 | heat shock 10kDa protein 1 |
| 背景介绍 | Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s). Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process. Cpn10 has been located in human platelets, but is also present in human maternal serum. It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy. |
| 生物功能 | Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. [UniProt] |
| 细胞定位 | Mitochondrion Matrix |
| 研究领域 | Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 11 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG20534 anti-Cpn 10 antibody WB image
Western blot: Rat brain extract stained with ARG20534 anti-Cpn 10 antibody at 1:1000 dilution.
