ARG24005
anti-Collagen XI antibody
anti-Collagen XI antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Bovine
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Collagen XI |
|---|---|
| 反应物种 | Bov |
| 应用 | ELISA, ICC/IF, IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Collagen XI |
| 抗原物种 | Bovine |
| 抗原 | Type XI collagen extracted from Bovine cartilage. |
| 偶联标记 | Un-conjugated |
| 別名 | STL2; COLL6; CO11A1; Collagen alpha-1(XI) chain |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: treat sections with 0.5% hyaluronidase at RT for 1hr before staining. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | COL11A1 |
|---|---|
| 全名 | collagen, type XI, alpha 1 |
| 背景介绍 | This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009] |
| 生物功能 | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
| 预测分子量 | 181 kDa |
| 翻译后修饰 | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. N-glycosylated. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
-
ARG24005 anti-Collagen XI antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Bovine cartilage tissue stained with ARG24005 anti-Collagen XI antibody.
