ARG23996
anti-Collagen VI antibody
anti-Collagen VI antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Collagen VI |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, ICC/IF, IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Collagen VI |
| 抗原物种 | Human |
| 抗原 | Type VI collagen extracted from Human placenta. |
| 偶联标记 | Un-conjugated |
| 別名 | OPLL; Collagen alpha-1(VI) chain |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: treat sections with 0.5% hyaluronidase at RT for 1hr before staining. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | COL6A1 |
| 全名 | collagen, type VI, alpha 1 |
| 背景介绍 | The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008] |
| 生物功能 | Collagen VI acts as a cell-binding protein. [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
| 预测分子量 | 109 kDa |
| 翻译后修饰 | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG23996 anti-Collagen VI antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human skin tissue stained with ARG23996 anti-Collagen VI antibody.
