ARG20791
anti-Collagen V antibody (Biotin), pre-adsorbed
anti-Collagen V antibody (Biotin), pre-adsorbed for ELISA,Electron microscopy,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Chicken,Pig
概述
| 产品描述 | Biotin-conjugated Goat Polyclonal antibody recognizes Collagen V |
|---|---|
| 反应物种 | Hu, Ms, Chk, Pig |
| 应用 | ELISA, EM, ICC/IF, IHC-Fr, IHC-P, WB |
| 特异性 | The antibody reacts with conformational determinants on type V collagen. The antibody is pre-adsorbed with Collagen types I, II, III, IV and VI, so the antibody may not react with Collagen types I, II, III, IV and VI. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Collagen V |
| 抗原物种 | Human |
| 抗原 | Collagen V |
| 偶联标记 | Biotin |
| 別名 | EDSC; Collagen alpha-1(V) chain |
应用说明
| 预吸附 | Collagen types I, II, III, IV and VI. | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 浓度 | 0.4 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | COL5A1 |
| 全名 | collagen, type V, alpha 1 |
| 背景介绍 | This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] |
| 生物功能 | Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. [UniProt] |
| 预测分子量 | 184 kDa |
| 翻译后修饰 | Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Sulfated on 40% of tyrosines. |
