ARG52245
anti-Clavesin antibody
anti-Clavesin antibody for ICC/IF,Western blot and Rat
Cancer antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Clavesin |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Clavesin |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | Clavesin-1; Retinaldehyde-binding protein 1-like 1; Cellular retinaldehyde-binding protein-like; CRALBPL; RLBP1L1 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|---|---|
| 应用说明 | Specific for the ~ 35 kDa clavesin 1/2 protein doublet in Western blots of Rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | PBS and 50% Glycerol |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CLVS1/2 |
| 全名 | clavesin 1 |
| 背景介绍 | Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008). |
| 研究领域 | Cancer antibody; Signaling Transduction antibody |
| 预测分子量 | 41 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG52245 anti-Clavesin antibody WB image
Western Blot: rat hippocampal homogenate showing specific immunolabeling of the ~35k clavesin protein stained with Clavesin antibody (ARG52245).
