ARG66835
anti-Claudin 2 antibody
anti-Claudin 2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Claudin 2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Claudin 2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide between aa. 181-230 of Human Claudin 2. |
| 偶联标记 | Un-conjugated |
| 別名 | Claudin-2; SP82 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol and 0.5% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CLDN2 |
| 全名 | claudin 2 |
| 背景介绍 | This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010] |
| 生物功能 | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. [UniProt] |
| 细胞定位 | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | The disulfide bond is necessary for pore formation, but is not required for correct protein trafficking. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG66835 anti-Claudin 2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human breast carcinoma tissue stained with ARG66835 anti-Claudin 2 antibody. The picture on the right is blocked with the synthetic peptide.
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ARG66835 anti-Claudin 2 antibody WB image
Western blot: Mouse kidney lysate stained with ARG66835 anti-Claudin 2 antibody at 1:1000 dilution.
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ARG66835 anti-Claudin 2 antibody WB image
Western blot: NIH/3T3 cell lysates stained with ARG66835 anti-Claudin 2 antibody. The lane on the right is blocked with the synthetic peptide.
