ARG42789
anti-Cip4 antibody
anti-Cip4 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cip4 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Cip4 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human Cip4. |
| 偶联标记 | Un-conjugated |
| 別名 | CIP4; Cdc42-interacting protein 4; Salt tolerant protein; STOT; HSTP; Thyroid receptor-interacting protein 10; STP; TR-interacting protein 10; hSTP; Protein Felic; TRIP-10 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | K562 | ||||
| 实际分子量 | ~ 85 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TRIP10 |
| 全名 | thyroid hormone receptor interactor 10 |
| 生物功能 | Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. [UniProt] |
| 细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9. Isoform 5: Cytoplasm, perinuclear region. [UniProt] |
| 预测分子量 | 68 kDa |
| 翻译后修饰 | Tyrosine phosphorylated. Also phosphorylated by PKA. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42789 anti-Cip4 antibody WB image
Western blot: K562 cell lysate stained with ARG42789 anti-Cip4 antibody at 1:1000 dilution.
