ARG22480
anti-Chymotrypsin antibody [4E1]
anti-Chymotrypsin antibody [4E1] for ELISA,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [4E1] recognizes Chymotrypsin This antibody recognizes human chymotrypsin-C, also known as chymotrypsin or caldecrin. Chymotrypsin is a 239 amino acid ~30 kDa protease with an additional 13 amino acid propeptide region and a 16 amino acid signal peptide.Variations in the CTRC gene has been associated with susceptibility to hereditary, pancreatitis (PCTT), a disease characterized by pancreatic inflammation and destruction of the parenchyma (Beer et al. 2013). |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ELISA, ICC/IF, IHC-Fr, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 4E1 |
| 同位型 | IgG3 |
| 靶点名称 | Chymotrypsin |
| 抗原物种 | Human |
| 抗原 | Purified human pancreatic chymotrypsin. |
| 偶联标记 | Un-conjugated |
| 別名 | ELA4; Chymotrypsin-C; CLCR; Caldecrin; EC 3.4.21.2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CTRC |
| 全名 | chymotrypsin C (caldecrin) |
| 背景介绍 | This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity. [UniProt] |
| 预测分子量 | 29 kDa |
