ARG55538
anti-ChAT antibody
anti-ChAT antibody for ICC/IF,Western blot and Human,Mouse
Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ChAT |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ChAT |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 98-128 (N-terminus) of Human ChAT. |
| 偶联标记 | Un-conjugated |
| 別名 | CMS1A; Choline acetylase; CHOACTase; CHOACTASE; EC 2.3.1.6; CMS6; Choline O-acetyltransferase; ChAT; CMS1A2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | NCI-H460 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CHAT |
| 全名 | choline O-acetyltransferase |
| 背景介绍 | This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010] |
| 生物功能 | Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. [UniProt] |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 83 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG55538 anti-ChAT antibody ICC/IF image
Immunofluorescence: NCI-H460 cells stained with ARG55538 anti-ChAT antibody (green). DAPI (blue) for nuclear staining.
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ARG55538 anti-ChAT antibody WB image
Western blot: 35 µg of NCI-H460 cell lysate stained with ARG55538 anti-ChAT antibody.
