ARG40174
anti-Cathepsin S antibody
anti-Cathepsin S antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
参考文献3
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cathepsin S |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Cathepsin S |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Cathepsin S. |
| 偶联标记 | Un-conjugated |
| 別名 | Cathepsin S; EC 3.4.22.27 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | U-87MG | ||||||
| 实际分子量 | 25 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CTSS |
| 全名 | cathepsin S |
| 背景介绍 | The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
| 生物功能 | Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
| 预测分子量 | 37 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG40174 anti-Cathepsin S antibody WB image
Western blot: U-87MG cell lysate stained with ARG40174 anti-Cathepsin S antibody.
文献引用
Interleukin-4 promotes the clearance of amyloid-β by monocyte through enhancing the recognition and intracellular processing of amyloid-β
WB / Human
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease
WB / Human
Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer's disease.
WB / Human
