ARG42664
anti-Cathepsin L + Cathepsin V + Cathepsin K + Cathepsin H antibody
anti-Cathepsin L + Cathepsin V + Cathepsin K + Cathepsin H antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Cathepsin L + Cathepsin V + Cathepsin K + Cathepsin H |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Cathepsin L + Cathepsin V + Cathepsin K + Cathepsin H |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human Cathepsin L+V+K+H. |
| 偶联标记 | Un-conjugated |
| 別名 | Major excreted protein; Cathepsin L; CATL; Cathepsin L1; EC 3.4.22.15; CTSL1; MEP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | HepG2 | ||||||||||
| 实际分子量 | ~ 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CTSL |
| 全名 | cathepsin L |
| 背景介绍 | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] |
| 生物功能 | Important for the overall degradation of proteins in lysosomes. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
| 预测分子量 | CTSL: 38 kDa CTSV: 37 kDa CTSK: 37 kDa CTSH: 37 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG42664 anti-Cathepsin L + Cathepsin V + Cathepsin K + Cathepsin H antibody WB image
Western blot: HepG2 cell lysate stained with ARG42664 anti-Cathepsin L + Cathepsin V + Cathepsin K + Cathepsin H antibody.
