ARG55171
anti-Caspase 5 antibody
anti-Caspase 5 antibody for ELISA,ICC/IF,Western blot and Human
Cell Biology and Cellular Response antibody; Cell Death antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Caspase 5 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, ICC/IF, WB |
| 特异性 | Depending on cell lines or tissues used, other cleavage products may be observed. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Caspase 5 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (14 aa) within aa. 170-220 of Human Caspase-5. |
| 偶联标记 | Un-conjugated |
| 別名 | Protease ICH-3; Caspase-5; Protease TY; CASP-5; EC 3.4.22.58; ICE; ICEREL-III; ICH-3; ICE(rel)III; rel |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Ramos Cell Lysate |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CASP5 |
| 全名 | caspase 5, apoptosis-related cysteine peptidase |
| 背景介绍 | Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1β. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma. | |
| 生物功能 | Mediator of programmed cell death (apoptosis). |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | The two subunits are derived from the precursor sequence by an autocatalytic mechanism. |
检测图片 (3) Click the Picture to Zoom In
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ARG55171 anti-Caspase 5 antibody WB image
Western blot: Ramos cells stained with ARG55171 anti-Caspase 5 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml dilution.
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ARG55171 anti-Caspase 5 antibody ICC/IF image
Immunocytochemistry: P815 cells stained with ARG55171 anti-Caspase 5 antibody at 2 ug/ml dilution.
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ARG55171 anti-Caspase 5 antibody ICC/IF image
Immunofluorescence: P815 cells stained with ARG55171 anti-Caspase 5 antibody at 2 ug/ml dilution.
