ARG45516
anti-Carma 3 antibody
anti-Carma 3 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Carma 3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Carma 3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Carma 3. |
| 偶联标记 | Un-conjugated |
| 別名 | CARD10; Caspase Recruitment Domain Family Member 10; CARMA3; BIMP1; Caspase Recruitment Domain-Containing Protein 10; CARD-Containing MAGUK Protein 3; Carma 3; Caspase Recruitment Domain Family, Member 10; Bcl10 Binding Protein And Activator Of NFKB; CARD-Containing MAGUK 3 Protein; IMD89 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 116 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P58660 Mouse Caspase recruitment domain-containing protein 10 Swiss-port # Q9BWT7 Human Caspase recruitment domain-containing protein 10 |
|---|---|
| 基因名称 | CARD10 |
| 全名 | Caspase Recruitment Domain Family Member 10 |
| 背景介绍 | The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008] |
| 生物功能 | Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 116 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45516 anti-Carma 3 antibody IHC-P image
Immunohistochemistry: Human bladder cancer stained with ARG45516 anti-Carma 3 antibody at 2 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody WB image
Western blot: Human Hacat stained with ARG45516 anti-Carma 3 antibody at 0.5 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45516 anti-Carma 3 antibody at 1 µg/10^6 cells dilution.
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ARG45516 anti-Carma 3 antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG45516 anti-Carma 3 antibody at 2 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45516 anti-Carma 3 antibody at 2 μg/ml dilution.
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ARG45516 anti-Carma 3 antibody WB image
Western blot: Mouse kidney stained with ARG45516 anti-Carma 3 antibody at 0.5 μg/ml dilution.
