ARG54629
anti-Calpastatin antibody [CSL1 5]
anti-Calpastatin antibody [CSL1 5] for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Neuroscience antibody
概述
| 产品描述 | Mouse Monoclonal antibody [CSL1 5] recognizes Calpastatin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, IHC-P, WB |
| 特异性 | This antibody specifically recognizes an epitope within domain III of human calpastatin. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | CSL1 5 |
| 同位型 | IgG1 |
| 靶点名称 | Calpastatin |
| 抗原物种 | Human |
| 抗原 | Recombinant human muscle-type calpastatin. |
| 偶联标记 | Un-conjugated |
| 別名 | Calpastatin; PLACK; Calpain inhibitor; Sperm BS-17 component; BS-17 |
应用说明
| 应用说明 | ELISA: 1 - 10 ug/ml with immobilized antigen. Western blot: 1 - 10 ug/ml, denaturing and non-denaturing conditions. Immunohistochemistry: 1 - 10 ug/ml, frozen tissue sections. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 10 mM PBS (pH 7.4) and 1% BSA |
| 稳定剂 | 1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CAST |
| 全名 | calpastatin |
| 背景介绍 | The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] |
| 生物功能 | Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Neuroscience antibody |
| 预测分子量 | 77 kDa |
| 翻译后修饰 | The N-terminus is blocked. |
