概述

产品描述	Rabbit Polyclonal antibody recognizes Calpastatin
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	Calpastatin
抗原物种	Human
抗原	Synthetic peptide of Human Calpastatin.
偶联标记	Un-conjugated
別名	Calpastatin; PLACK; Calpain inhibitor; Sperm BS-17 component; BS-17

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	A549

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 12380 Mouse CAST GeneID: 25403 Rat CAST GeneID: 831 Human CAST Swiss-port # P20810 Human Calpastatin Swiss-port # P27321 Rat Calpastatin Swiss-port # P51125 Mouse Calpastatin More
基因名称	CAST
全名	calpastatin
背景介绍	The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
生物功能	Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. [UniProt]
预测分子量	77 kDa
翻译后修饰	The N-terminus is blocked.

检测图片 (1) Click the Picture to Zoom In