ARG46068
anti-Calcium Sensing Receptor antibody
anti-Calcium Sensing Receptor antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Calcium Sensing Receptor |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Calcium Sensing Receptor |
| 抗原物种 | Human |
| 抗原 | A 15 amino acid synthetic peptide within the first 50 amino acids of human Calcium Sensing Receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | CASR; Extracellular calcium-sensing receptor; EIG8; FHH; PCaR1; CAR; HHC1; GPRC2A; Parathyroid cell calcium-sensing receptor 1; HHC; PCAR1; CaSR; HYPOC1; FIH; NSHPT |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 115,125 kDa |
属性
| 纯化 | Affinity chromatography purified |
|---|---|
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CASR |
| 全名 | calcium-sensing receptor |
| 背景介绍 | The calcium sensing receptor (CaSR) has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. Several disorders of calcium homeostasis have been linked to mutations in the CaSR. These include familial hypocalciuric hypercalcemia (FHH), neonatal severe hyperparathyroidism (NSHPT), and autosomal dominant hypocalemia (ADHypo). |
| 细胞定位 | Cytoplasm, Membrane |
| 预测分子量 | 101,120 kDa |
| 翻译后修饰 | N-glycosylated. Ubiquitinated by RNF19A; which induces proteasomal degradation. |
检测图片 (2) Click the Picture to Zoom In
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ARG46068 anti-Calcium Sensing Receptor antibody IHC-P image
Immunohistochemistry: Human kidney stained with ARG46068 anti-Calcium Sensing Receptor antibody.
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ARG46068 anti-Calcium Sensing Receptor antibody WB image
Western blot: EL4 stained with ARG46068 anti-Calcium Sensing Receptor antibody.
