ARG45706

anti-Cadherin 15 antibody

anti-Cadherin 15 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes Cadherin 15
反应物种 Hu, Ms, Rat
应用 FACS, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Cadherin 15
抗原物种 Human
抗原 Recombinant protein containing to human Cadherin 15.
偶联标记 Un-conjugated
別名 CDH15; cadherin 15, type 1, M-cadherin (myotubule); CDHM; CDH14; MRD3; MCAD; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin; CDH3

应用说明

应用建议
应用 推荐稀释比
FACS1 - 3 µg/10^6 cells
IHC-P2-5 μg/ml
WB0.25-0.5 μg/ml
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 130 kDa

属性

形式 Liquid
纯化 Affinity purified
缓冲液 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose.
稳定剂 4% Trehalose
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 1013 Human CDH15

GeneID: 12555 Mouse CDH15

Swiss-port # P33146 Mouse Cadherin-15

Swiss-port # P55291 Human Cadherin-15

基因名称 CDH15
全名 cadherin 15, type 1, M-cadherin (myotubule)
背景介绍 This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008]
生物功能 Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation. [UniProt]
细胞定位 Cell membrane; Single-pass type I membrane protein. [UniProt]
预测分子量 89 kDa
翻译后修饰 Cleavage on pair of basic residues; Glycoprotein. [UniProt]

检测图片 (6) Click the Picture to Zoom In

  • ARG45706 anti-Cadherin 15 antibody WB image

    Western blot: Hela stained with ARG45706 anti-Cadherin 15 antibody at 0.5 μg/ml dilution.

  • ARG45706 anti-Cadherin 15 antibody FACS image

    Flow Cytometry: C2C12 stained with ARG45706 anti-Cadherin 15 antibody at 1 µg/10^6 cells dilution.

  • ARG45706 anti-Cadherin 15 antibody IHC-P image

    Immunohistochemistry: Rat skeletal muscle stained with ARG45706 anti-Cadherin 15 antibody at 2 μg/ml dilution.

  • ARG45706 anti-Cadherin 15 antibody WB image

    Western blot: L6 stained with ARG45706 anti-Cadherin 15 antibody at 0.5 μg/ml dilution.

  • ARG45706 anti-Cadherin 15 antibody IHC-P image

    Immunohistochemistry: Mouse skeletal muscle stained with ARG45706 anti-Cadherin 15 antibody at 2 μg/ml dilution.

  • ARG45706 anti-Cadherin 15 antibody WB image

    Western blot: C2C12 stained with ARG45706 anti-Cadherin 15 antibody at 0.5 μg/ml dilution.