ARG67127
anti-CXCR7 / CD187 antibody
anti-CXCR7 / CD187 antibody for ICC/IF,Western blot and Human,Mouse,Rat,Monkey
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CXCR7 / CD187 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Mk |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CXCR7 / CD187 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human CXCR7 / CD187 (a.a. 311-360). |
| 偶联标记 | Un-conjugated |
| 別名 | ACKR3; Atypical Chemokine Receptor 3; GPR159; RDC1; Chemokine Orphan Receptor 1; CMKOR1; CXCR7; G-Protein Coupled Receptor RDC1 Homolog; Chemokine (C-X-C Motif) Receptor 7; C-X-C Chemokine Receptor Type 7 ; G-Protein Coupled Receptor 159; CXC-R7; CXCR-7; RDC-1; G Protein-Coupled Receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography using epitope-specific immunogen. |
| 缓冲液 | PBS with 0.02% Sodium azide, 0.5% BSA and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 5% BSA and 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACKR3 |
| 全名 | Atypical Chemokine Receptor 3 |
| 背景介绍 | This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008] |
| 生物功能 | Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. [Uniprot] |
| 细胞定位 | Cell membrane, Endosome, Membrane. [Uniprot] |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG67127 anti-CXCR7 / CD187 antibody ICC/IF image
Immunofluorescence: COS7 stained with ARG67127 anti-CXCR7 / CD187 antibody.
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ARG67127 anti-CXCR7 / CD187 antibody WB image
Western blot: COS7 stained with ARG67127 anti-CXCR7 / CD187 antibody at 1:2000 dilution.
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ARG67127 anti-CXCR7 / CD187 antibody WB image
Western blot: RAW264.7 stained with ARG67127 anti-CXCR7 / CD187 antibody at 1:2000 dilution.
