ARG54407
anti-CXCR6 / Bonzo antibody
anti-CXCR6 / Bonzo antibody for Western blot and Human
Immune System antibody; Microbiology and Infectious Disease antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CXCR6 / Bonzo |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | This antibody recognizes full-length Bonzo (40 kD). |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CXCR6 / Bonzo |
| 抗原物种 | Human |
| 抗原 | Peptide corresponding to aa 319-338 at the C-terminus of human Bonzo. The sequence of this peptide is identical to those of macaque and African green monkey. |
| 偶联标记 | Un-conjugated |
| 別名 | CDw186; BONZO; STRL33; CXCR-6; TYMSTR; C-X-C chemokine receptor type 6; G-protein coupled receptor STRL33; CD antigen CD186; G-protein coupled receptor bonzo; CD186; CXC-R6 |
应用说明
| 应用说明 | Western blot: use at 1:1,000 dilution. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|---|
| 阳性对照 | SW1353 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunoaffinity chroma-tography |
| 缓冲液 | PBS (pH 7.4) and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CXCR6 |
| 全名 | chemokine (C-X-C motif) receptor 6 |
| 背景介绍 | Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors in addition to CD4 to infect target cells. Some G protein-coupled receptors in the chemokine receptor family, including CCR5, CXCR4, CCR3, and CCR2b, have previously been identified as HIV coreceptors. An orphan G protein-coupled receptor designated Bonzo was recently cloned and identified as a HIV-1 and -2 and SIV coreceptor (also called STRL33 and TYMSTR). The messenger RNA for Bonzo is expressed in lymphoid tissues and activated peripheral blood lymphocytes. |
| 生物功能 | Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. [UniProt] |
| 研究领域 | Immune System antibody; Microbiology and Infectious Disease antibody |
| 预测分子量 | 39 kDa |
