ARG45969
anti-CX3CR1 antibody [2A9-1] (PE-Cyanine 7)
anti-CX3CR1 antibody [2A9-1] (PE-Cyanine 7) for Flow cytometry and Human,Monkey
概述
| 产品描述 | PE-Cyanine 7-conjugated Rat Monoclonal antibody [2A9-1] recognizes CX3CR1 |
|---|---|
| 反应物种 | Hu, Mk |
| 应用 | FACS |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 2A9-1 |
| 同位型 | IgG2b kappa |
| 靶点名称 | CX3CR1 |
| 抗原物种 | Human |
| 抗原 | Human CX3CR1-transfected cell line. |
| 偶联标记 | PE-Cyanine 7 |
| 別名 | chemokine (C-X3-C motif) receptor 1; CMK-BRL1; GPR13; CX3CR1; CMK-BRL-1; C-X3-C CKR-1; CX3C chemokine receptor 1; V28; CCRL1; GPRV28; CMKBRL1; G-protein coupled receptor 13; CMKDR1; Beta chemokine receptor-like 1; Fractalkine receptor |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-cyanine 7 (PE-Cy™7) under optimum conditions. The conjugate was purified by size-exclusion chromatography. |
| 缓冲液 | PBS and 15 mM Sodium azide. |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CX3CR1 |
| 全名 | chemokine (C-X3-C motif) receptor 1 |
| 背景介绍 | CX 3 CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, murine, and rat CX 3 CR1 have been cloned and designated V28 and CMKBRL1, CX 3 CR1, and RBS11, respectively. This transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and was renamed CX 3 CR1. Recently, CX 3 CR1was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by factalkine. CX 3 CR1 mediates leukocyte migration and adhesion and is expressed in a variety of human tissues and cell lines. |
| 生物功能 | Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. [UniProt] |
| 细胞定位 | Cell membrane; Membrane. [UniProt] |
| 翻译后修饰 | This protein is not N-glycosylated which is unusual for G-protein-coupled receptors. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
-
ARG45969 anti-CX3CR1 antibody [2A9-1] (PE-Cyanine 7) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG45969 anti-CX3CR1 antibody [2A9-1] (PE-Cyanine 7) at 0.56 μg/ml dilution.
-
ARG45969 anti-CX3CR1 antibody [2A9-1] (PE-Cyanine 7) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG45969 anti-CX3CR1 antibody [2A9-1] (PE-Cyanine 7) at 0.56 μg/ml dilution.
