ARG59641
anti-CTNS antibody
anti-CTNS antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CTNS |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu, Rat, Cow, Dog, Hrs, Pig, Rb |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CTNS |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide around the middle region of Mouse CTNS. (within the following region: GQVTVFLHGNHSNQTCPRIRFLVIHSRIVSIINQVIGWIYFMAWSVSFYP) |
| 偶联标记 | Un-conjugated |
| 別名 | Cystinosin; PQLC4; CTNS-LSB |
应用说明
| 预测反应性说明 | Predicted Homology Based On Immunogen Sequence: Cow: 93%; Dog: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 92%; Rabbit: 85%; Rat: 92% | ||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CTNS |
| 全名 | cystinosin, lysosomal cystine transporter |
| 背景介绍 | This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009] |
| 生物功能 | Cystine/H(+) symporter thought to transport cystine out of lysosomes. Plays an important role in melanin synthesis, possibly by preventing melanosome acidification and subsequent degradation of tyrosinase TYR. [UniProt] |
| 细胞定位 | Isoform 1: Lysosome membrane; Multi-pass membrane protein. Melanosome. Isoform 2: Lysosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 42 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59641 anti-CTNS antibody WB image
Western blot: Mouse lung lysate stained with ARG59641 anti-CTNS antibody at 1 µg/ml dilution.
