ARG67163
anti-CSN5A + CSN5B antibody
anti-CSN5A + CSN5B antibody for Western blot and Arabidopsis
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes CSN5A and CSN5B |
|---|---|
| 反应物种 | Arabi |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CSN5A + CSN5B |
| 抗原物种 | Plant |
| 抗原 | Synthetic peptide corresponding to center region of arabidopsis thaliana CSN5A/B protein. |
| 偶联标记 | Un-conjugated |
| 別名 | AJH1; CSN5B; COP9 signalosome complex subunit 5a; Signalosome subunit 5a; Jun activation domain-binding homolog 1; AJH2; CSN5A; COP9 signalosome complex subunit 5b; Signalosome subunit 5b; Jun activation domain-binding homolog 2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CSN5A; CSN5B |
|---|---|
| 全名 | COP9 signalosome 5A + COP9 signalosome 5B |
| 背景介绍 | CSN5A: AJH1 encodes a protein similar to JAB1, a specific mammalian coactivator of AP-1 transcription. Encodes a subunit of the COP9 complex that is involved in protein deneddylation. Plants with mutations in CSN5A and CSN5B have a de-etiolated phenotype. CSN5B: Encodes a subunit of the COP9 complex, similar to JAB1, a specific mammalian coactivator of AP-1 transcription. Involved in protein deneddylation. Double mutants with CSN5A are constitutively photomorphogenic (de-etiolated) and have abnormal auxin responses. |
| 生物功能 | The CSN complex is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. [UniProt] The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. [UniProt] Involved in CSN's deneddylation/derubylation activity. [UniProt] |
| 细胞定位 | Cytoplasm, Nucleus. [UniProt] |
| 产品亮点 | Related news: Antibodies for Arabidopsis thaliana; |
| 预测分子量 | 39;40 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG67163 anti-CSN5A + CSN5B antibody WB image
Western blot: Arabidopsis thaliana stained with ARG67163 anti-CSN5A + CSN5B antibody.
