ARG42097
anti-CROT / COT antibody
anti-CROT / COT antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Goat Polyclonal antibody recognizes CROT / COT |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Dog |
| 应用 | IHC-P |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | CROT / COT |
| 抗原物种 | Rat |
| 抗原 | Synthetic peptide around the internal region of Rat CROT / COT. (NYFKTESEGHCPTH) (NP_114193.1) |
| 偶联标记 | Un-conjugated |
| 別名 | Peroxisomal carnitine O-octanoyltransferase; COT; EC 2.3.1.137 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UKG9 Human Peroxisomal carnitine O-octanoyltransferase |
|---|---|
| 基因名称 | CROT |
| 全名 | carnitine O-octanoyltransferase |
| 背景介绍 | This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
| 生物功能 | Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester. [UniProt] |
| 细胞定位 | Peroxisome. [UniProt] |
| 预测分子量 | 70 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG42097 anti-CROT / COT antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42097 anti-CROT / COT antibody at 5 µg/ml dilution followed by AP-staining.
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ARG42097 anti-CROT / COT antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42097 anti-CROT / COT antibody at 5 µg/ml dilution followed by AP-staining.
